The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 28, 2018

Filed:

Feb. 26, 2016
Applicant:

East Carolina University, Greenville, NC (US);

Inventors:

Cheng Chen, Greenville, NC (US);

T. Bruce Ferguson, Jr., Raleigh, NC (US);

Zhiyong Peng, Greenville, NC (US);

Kenneth Michael Jacobs, Greenville, NC (US);

Assignee:

East Carolina University, Greenville, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/02 (2006.01); A61B 5/026 (2006.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/0261 (2013.01); A61B 5/0077 (2013.01); A61B 5/721 (2013.01); A61B 5/7207 (2013.01); A61B 5/7271 (2013.01); A61B 2576/00 (2013.01);
Abstract

Some embodiments of the present inventive concept provide a system that uses two wavelengths of differential transmittance through a sample to apply laser speckle or laser Doppler imaging. A first of the two wavelengths is within the visible range that has zero or very shallow penetration. This wavelength captures the anatomical structure of tissue/organ surface and serves as a position marker of the sample but not the subsurface movement of blood flow and perfusion. A second wavelength is in the near Infra-Red (NIR) range, which has much deeper penetration. This wavelength reveals the underlying blood flow physiology and correlates both to the motion of the sample and also the movement of blood flow and perfusion. Thus, true motion of blood flow and perfusion can be derived from the NIR imaging measurement without being affected by the motion artifact of the target.


Find Patent Forward Citations

Loading…