The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 21, 2018
Filed:
Mar. 31, 2015
Biocrates Life Sciences Ag, Innsbruck, AT;
Idcgs Clinica DE Diagnosticos Medicos, Vila Mariana, Sao Paulo, BR;
Centro DE Genomas, Sao Paulo, BR;
Ismael Dale Cotrim Guerreiro Da Silva, Sao Paulo, BR;
Edson Guimaraes Loturco, Sao Paulo, BR;
Ricoardo Soubie Diaz, Sao Paulo, BR;
Therese Koal, Innsbruck, AT;
Biocrates Life Sciences AG, , AT;
IDCGS Clinica de Diagnosticos Medicos, , BR;
Centro de Genomas, , BR;
Abstract
The present invention relates to metabolic biomarker sets for assessing HIV. In preferred embodiments, the present invention relates to the use of biomarker sets for screening and/or diagnosing HIV infection, for prediction of immunologic response of a mammalian subject to antiretroviral therapy and/or prognosis of HIV disease progression, and for monitoring of HIV disease activity in a mammalian subject. In other embodiments, the invention relates to methods for screening and/or diagnosing HIV infection, for prediction of immunologic response of a mammalian subject to antiretroviral therapy and/or prognosis of HIV disease progression, and for monitoring of HIV disease activity in a mammalian subject, as well as to a kit adapted to carry out the methods. By employing the specific biomarkers and the method according to the present invention it becomes possible to more properly and reliably assess HIV. In particular, it becomes possible to screen for and diagnose HIV in a patient with high accuracy and predict early in advance the patient's therapeutic response to antiretroviral therapy.