The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 21, 2018

Filed:

Jan. 30, 2015
Applicants:

University of Copenhagen, Copenhagen, DK;

Danmarks Tekniske Universitet, Lyngby, DK;

Evolva SA, Reinach, CH;

Inventors:

Björn Hamberger, Kastrup, DK;

Birger Lindberg Møller, Brønshøj, DK;

Eirini Pateraki, Vallensbeak Strand, DK;

Johan Andersen-Ranberg, Copenhagen, DK;

Niels Bjerg Jensen, Kastrup, DK;

Assignees:

University of Copenhagen, Copenhagen, DK;

Danmarks Tekniske Universitet, Lyngby, DK;

Evolva SA, Renach, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/04 (2006.01); C12P 17/06 (2006.01); C12N 9/02 (2006.01); C12P 5/00 (2006.01);
U.S. Cl.
CPC ...
C12P 17/06 (2013.01); C12N 9/0071 (2013.01); C12P 5/007 (2013.01); C12Y 114/14001 (2013.01);
Abstract

The invention described materials and methods for producing oxidized 13R-MO, such as forskolin. In particular, the invention describes P450s involved in oxidation of 13R-MO including CYP76AH8, CYP76AH11, CYP76AH15, CYP76AH17, CYP71D381 and CYP76AH9. Host organisms expressing one or more of these P450s are useful in the production of oxidized 13R-MO.


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