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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10053712 B1

PDFFull Text
Date of Patent:
Aug. 21, 2018

Filed:

Dec. 10, 2014

Use of enzymes which catalyze pyruvate synthesis from formate and acetyl-coa and bacteria expressing same

Applicant:

Yeda Research and Development Co. Ltd., Rehovot, IL;

Inventors:

Arren Bar-Even, Tel-Aviv, IL;

Ron Milo, Kfar-Saba, IL;

Elad Noor, Rehovot, IL;

Lior Zelcbuch, Rehovot, IL;

Assignee:

Yeda Research and Development Co. Ltd., Rehovot, IL;

Attorney:
Primary Examiner:

Kagnew H Gebreyesus

Int. Cl.
CPC ...
C12P 7/40 (2006.01); C12N 1/20 (2006.01); C12N 9/10 (2006.01); C12N 15/52 (2006.01); C12P 5/00 (2006.01); C12P 5/02 (2006.01); C12P 7/06 (2006.01); C12P 7/16 (2006.01); C12P 7/26 (2006.01); C12P 7/64 (2006.01);
U.S. Cl.
CPC ...
C12P 7/40 (2013.01); C12N 1/20 (2013.01); C12N 9/1029 (2013.01); C12N 15/52 (2013.01); C12P 5/007 (2013.01); C12P 5/023 (2013.01); C12P 5/026 (2013.01); C12P 7/06 (2013.01); C12P 7/16 (2013.01); C12P 7/26 (2013.01); C12P 7/649 (2013.01); C12Y 203/01054 (2013.01); Y02E 50/343 (2013.01);
Abstract

An isolated microorganism is disclosed being genetically modified to express pyruvate formate lyase (PFL) or 2-ketobutyrate formate lyase, wherein acetyl-CoA of the microorganism is converted to pyruvate in the presence of formate in a single step reaction, wherein the net flux of the reaction is in the direction of pyruvate synthesis. Uses of the microorganism and products comprising same are also disclosed.

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Bar-Even, Arren. (2018). Use of enzymes which catalyze pyruvate synthesis from formate and acetyl-coa and bacteria expressing same (U.S. Patent No. 10053712). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10053712

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