The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 21, 2018

Filed:

Nov. 20, 2013
Applicant:

Nankai University, Tianjin, CN;

Inventors:

Huiqi Zhang, Tianjin, CN;

Yue Ma, Tianjin, CN;

Ying Zhang, Tianjin, CN;

Guoqing Pan, Tianjin, CN;

Assignee:

NANKAI UNIVERSITY, Tianjin, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08F 267/06 (2006.01); G01N 33/543 (2006.01); C08F 2/38 (2006.01); C08F 220/06 (2006.01); C08F 222/14 (2006.01); C08F 226/06 (2006.01);
U.S. Cl.
CPC ...
C08F 267/06 (2013.01); C08F 2/38 (2013.01); C08F 220/06 (2013.01); C08F 222/14 (2013.01); C08F 226/06 (2013.01); G01N 33/54346 (2013.01); C08F 2438/03 (2013.01); G01N 2600/00 (2013.01);
Abstract

This invention provides molecularly imprinted polymer nanoparticles compatible with biological samples, and in particular pure biological samples and a preparation method thereof. Said molecularly imprinted polymer nanoparticles have a crosslinking degree exceeding 50%, a particle diameter of 10 to 500 nm, hydrophilic polymer brushes on its surfaces and can be prepared by introducing appropriate hydrophilic macromolecular chain transfer agents into reversible addition-fragmentation chain transfer (RAFT) precipitation polymerization systems through the one-pot synthesis. The preparation method is simple, features a broad range of application and yields a pure product. The obtained hydrophilic molecularly imprinted polymer nanoparticles have prospects for a wide range of application in biological sample analysis, medical clinical immune analysis, food and environmental monitoring, biomimetic sensors, etc.


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