The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 21, 2018

Filed:

May. 26, 2014
Applicant:

Promis Neurosciences Inc., Toronto, CA;

Inventors:

Marni Diane Uger, Richmond Hill, CA;

Veronica Ciolfi, Brampton, CA;

Neil R. Cashman, Vancouver, CA;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); G01N 33/566 (2006.01); A61K 47/48 (2006.01); G01N 33/68 (2006.01); A61K 49/00 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61K 39/0005 (2013.01); A61K 47/48561 (2013.01); A61K 49/001 (2013.01); C07K 16/2872 (2013.01); G01N 33/566 (2013.01); G01N 33/56966 (2013.01); G01N 33/6893 (2013.01); A61K 2039/55566 (2013.01); C07K 2317/21 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); G01N 2333/70578 (2013.01);
Abstract

Provided herein are an exogenous antibody that binds selectively to a misfolded form of human FasR, and methods and uses for said antibody. Specifically disclosed is the antibody designated AMF 3a-118 which selectively binds the peptide represented by LHHDGQFCH (SEQ ID NO:2) and the antibody designated AMF 3d-19 which selectively binds the peptide represented by NSTVCEH (SEQ ID NO:5).


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