The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 21, 2018

Filed:

Nov. 30, 2015
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Zhijian Liu, Kendall Park, NJ (US);

Nobuyoshi Yasuda, Mountainside, NJ (US);

Lu Yang, San Diego, CA (US);

Artis Klapars, Edison, NJ (US);

Kevin R. Campos, Berkeley Heights, NJ (US);

Mikhail Reibarkh, Cranford, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/08 (2006.01); C07F 7/02 (2006.01); C07F 7/10 (2006.01); C07F 7/18 (2006.01);
U.S. Cl.
CPC ...
C07D 471/08 (2013.01); C07F 7/10 (2013.01); C07F 7/1868 (2013.01);
Abstract

The present invention relates to processes for preparing compounds of Formula I. Such compounds include interme-diates in the manufacture of 7-oxo-1,6-diazabicyclo[3.2.1 ]octane-2-carboxamide beta-lactamase inhibitors such as (2S,5R)-7-oxo-N-5 piperidin-4-yl-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide. The present invention also relates to novel intermediates formed i these processes. The present invention relates to a process for preparing a compound of Formula I or a pharmaceutically acceptable salt thereof.


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