The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 21, 2018
Filed:
May. 21, 2015
Korea Research Institute of Chemical Technology, Daejeon, KR;
Chang Soo Yun, Daejeon, KR;
Hyoung Rae Kim, Daejeon, KR;
Sung Yun Cho, Daejeon, KR;
Hee Jung Jung, Daejeon, KR;
Kwangho Lee, Daejeon, KR;
Chong Hak Chae, Daejeon, KR;
Chong Ock Lee, Seoul, KR;
Chi Hoon Park, Daejeon, KR;
Pilho Kim, Daejeon, KR;
Jong Yeon Hwang, Jeollabuk-do, KR;
Jae Du Ha, Daejeon, KR;
Sun Joo Ahn, Daejeon, KR;
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, Daejeon, KR;
Abstract
The present invention relates to a pyrimidine-2,4-diamine derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition for prevention or treatment of cancer comprising the same as an effective ingredient. A compound according to the present invention has the good effect of inhibiting anaplastic lymphoma kinase (ALK) activity, whereby a therapeutic effect on cancer cells having an anaplastic lymphoma kinase (ALK) fusion protein such as EML4-ALK, NPM-ALK, etc. can be enhanced and it is expected that a recurrence of cancer will be effectively inhibited. As such, the compound can be effectively used in a pharmaceutical composition for prevention or treatment of cancer.