The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 21, 2018

Filed:

Jan. 18, 2007
Applicants:

Noriko Koizumi, Kyoto, JP;

Shigeru Kinoshita, Osaka, JP;

Yuji Sakamoto, Kobe, JP;

Inventors:

Noriko Koizumi, Kyoto, JP;

Shigeru Kinoshita, Osaka, JP;

Yuji Sakamoto, Kobe, JP;

Assignee:

SENJU PHARMACEUTICAL CO., LTD., Osaka-shi, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A01N 63/00 (2006.01); C12N 5/07 (2010.01); C12N 5/071 (2010.01); C12N 5/16 (2006.01); C12N 5/0793 (2010.01); C12N 5/0789 (2010.01); A61L 27/38 (2006.01); A61L 27/24 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3839 (2013.01); A61L 27/24 (2013.01); A61L 27/3808 (2013.01); A61L 2430/16 (2013.01);
Abstract

The present invention provides a graft more suitable for the transplantation of corneal endothelial cells and an application method thereof. Specifically, the present invention provides a corneal endothelial preparation capable of cell proliferation in vivo, which contains a substrate and a corneal endothelial cell layer cultured on the substrate, and a treatment method of a disease selected from the group consisting of bullous keratopathy, corneal edema, corneal leukoma and corneal endothelial inflammation, which includes a step of transplanting the preparation to patients. As the substrate, collagen is used.


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