The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 21, 2018

Filed:

Jul. 03, 2014
Applicant:

Wayne State University, Detroit, MI (US);

Inventors:

Weiping Ren, Westland, MI (US);

Wei Song, Warren, MI (US);

Assignee:

WAYNE STATE UNIVERSITY, Detroit, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61L 27/12 (2006.01); A61K 9/50 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01);
U.S. Cl.
CPC ...
A61L 27/12 (2013.01); A61K 9/1652 (2013.01); A61K 9/5073 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 2400/06 (2013.01); A61L 2430/02 (2013.01); A61L 2430/34 (2013.01);
Abstract

The present invention describes an injectable calcium polyphosphate (CPP) gel with dense structure, which can be applied as injectable bone void filler in medical field, such as orthopedic and dental applications. Amorphous CPP powder with fine particle size (<75 pm) can be completely dissolved in water, forming a homogeneous gelation phase separated from water phase. This homogeneous CPP gel with disentangled inorganic polyphosphate chains shows viscoelasticity and superior adhesion to natural bone, metal implant surfaces and other ceramic material surfaces. The CPP gel is biomimetic and biodegradable with strong osteoconductivity and osteoinductivity. The manufacturing procedure is easy and reproducible. The mechanical strength of CPP gel is controllable by modifications, such as sintering, incorporation of other biomaterials, etc.


Find Patent Forward Citations

Loading…