The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 21, 2018
Filed:
Jun. 12, 2015
Applicant:
Changchun Huapu Biotechnology Co., Ltd., Changchun, Jilin Province, CN;
Inventors:
Ligong Wang, Beijing, CN;
Yan Shao, Beijing, CN;
Assignee:
Changchun Huapu Biotechnology Co., LTD., Changchun, CN;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61K 39/095 (2006.01); A61K 39/02 (2006.01); A61K 39/385 (2006.01); A61K 39/29 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/292 (2013.01); A61K 39/39 (2013.01); C12N 7/00 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55561 (2013.01); C12N 2730/10134 (2013.01);
Abstract
The present invention provides a pharmaceutical composition for inducing immune response in a subject, comprising: (a) an antigen with a concentration ranging from 1 μg/ml to 100 μg/ml; (b) CpG oligonucleotides having a sequence of 5'-tcgacgttcgtcgttcgtcgttc-3′, with a concentration ranging from 25 μg/ml to 500 μg/ml, and (c) an aluminum adjuvant with a concentration ranging from 25 μg/ml to 500 μg/ml. Such pharmaceutical composition can induce or boost immune response against antigen in the subject.