The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 21, 2018

Filed:

Oct. 19, 2010
Applicants:

Regine Sitruk-ware, New York, NY (US);

Michael Maria Helmut Schumacher, Kremlin-Bicêtre, FR;

Roberta Brinton, Rancho Palos Verdes, CA (US);

Martine El-etr, Paris, FR;

Abdelmouman Ghoumari, Antony, FR;

Rachida Guennoun, Villejuif, FR;

Inventors:

Regine Sitruk-Ware, New York, NY (US);

Michael Maria Helmut Schumacher, Kremlin-Bicêtre, FR;

Roberta Brinton, Rancho Palos Verdes, CA (US);

Martine El-Etr, Paris, FR;

Abdelmouman Ghoumari, Antony, FR;

Rachida Guennoun, Villejuif, FR;

Assignee:

The Population Council, Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/567 (2006.01); A61K 31/565 (2006.01); A61K 31/00 (2006.01); A61K 31/57 (2006.01); A61K 31/573 (2006.01); A61K 31/575 (2006.01); A61K 31/585 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/565 (2013.01); A61K 31/00 (2013.01); A61K 31/57 (2013.01); A61K 31/573 (2013.01); A61K 31/575 (2013.01); A61K 31/585 (2013.01); A61K 45/06 (2013.01);
Abstract

Methods for treating neurodegeneration and/or myelination in patients are disclosed comprising treating the patient with a progestin compound which exerts binding to progesterone receptors and elicits progesterone-receptor-induced biological responses without interacting with the androgen receptor and without inducing androgen or glucocorticoid biological responses at a dosage sufficient to prevent or reduce neurodegeneration. The progestin compound preferably comprises 16-methylene-17α-acetoxy-19-norpregn-4-ene-3,20-dione, and the methods include combining the progestin compound with an estrogen compound to provide both contraception and treatment for myelin repair and neurodegeneration.


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