The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 2018
Filed:
Dec. 23, 2016
Case Western Reserve University, Cleveland, OH (US);
Anant Madabhushi, Shaker Heights, OH (US);
Xiangxue Wang, Cleveland, OH (US);
Vamsidhar Velcheti, Pepper Pike, OH (US);
Case Western Reserve University, Cleveland, OH (US);
Abstract
Methods, apparatus, and other embodiments associated with predicting non-small cell lung cancer (NSCLC) patient response to adjuvant chemotherapy therapy using radiomic features extracted from digitized hematoxylin and eosin (H&E) stained slides of a region of tissue demonstrating NSCLC. One example apparatus includes an image acquisition circuit that acquires an H&E image of a region of tissue demonstrating NSCLC pathology, a segmentation circuit that segments a region of interest (ROI) from the diagnostic radiological image, a feature extraction that extracts a set of discriminative features from the ROI, and a classification circuit that generates a probability that the ROI will experience NSCLC recurrence. The classification circuit may compute a quantitative continuous image-based risk score based on the probability or the image. A prognosis or treatment plan may be provided based on the quantitative continuous image-based risk score.