The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 2018
Filed:
Aug. 04, 2017
Richard Antonius Jozef Janssen, Leiden, NL;
Annemarie Nicolette Lekkerkerker, Palo Alto, CA (US);
Thomas Van ES, Voorschoen, NL;
Johannes Melchior Petrus Stallen, Leiden, NL;
Richard Antonius Jozef Janssen, Leiden, NL;
Annemarie Nicolette Lekkerkerker, Palo Alto, CA (US);
Thomas Van Es, Voorschoen, NL;
Johannes Melchior Petrus Stallen, Leiden, NL;
GALAPAGOS NV, Mechelen, BE;
Abstract
The present invention relates to methods and assays for identifying agents useful in the treatment of fibrotic conditions. The invention provides polypeptide and nucleic acid TARGETs, siRNA sequences based on these TARGETs and antibodies against the TARGETs. The invention is further related to pharmaceutical composition comprising siRNA sequences based on the TARGETs and antibodies against the TARGETs for use in the treatment of fibrotic conditions. The invention further provides in vitro methods for reduction or inhibition of macrophage differentiation into alternatively-activated macrophages (M2).
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile