The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 14, 2018

Filed:

Nov. 11, 2015
Applicant:

Sintef Tto As, Trondheim, NO;

Inventors:

Hanne Jørgensen, Trondheim, NO;

Havard Sletta, Trondheim, NO;

Trond Erling Ellingsen, Trondheim, NO;

Espen Fjaervik, Trondheim, NO;

Kristin Fløgstad Degnes, Trondheim, NO;

Geir Klinkenberg, Heimdal, NO;

Per Bruheim, Trondheim, NO;

Sergey Zotchev, Trondheim, NO;

Assignee:

SINTEF TTO AS, Trondheim, NO;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 225/02 (2006.01); C12N 15/52 (2006.01); C07K 14/36 (2006.01); C12P 17/10 (2006.01); C12R 1/465 (2006.01); C12P 19/62 (2006.01);
U.S. Cl.
CPC ...
C12N 15/52 (2013.01); C07D 225/02 (2013.01); C07K 14/36 (2013.01); C12P 17/10 (2013.01); C12R 1/465 (2013.01); C12P 19/62 (2013.01);
Abstract

A nucleic acid molecule comprises a nucleotide sequence: as shown in SEQ ID No. 1, which is the complement of SEQ ID No. 1, which is degenerate with SEQ ID No. 1, or which has at least 85% sequence identity with SEQ ID No. 1, or which is a part of such a sequence. The nucleic acid molecule encodes or is a complementary to a nucleic acid molecule encoding one or more polypeptides, or comprises or is complementary to a nucleic acid molecule comprising one or more genetic elements, having functional activity in the synthesis of a polyketide-based or macrolactam molecule. The nucleic acid molecule may be used to prepare a modified BE-14106 biosynthetic gene cluster for the preparation of a modified BE-14106 molecule.


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