The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 2018
Filed:
Dec. 09, 2016
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Hao Yin, Cambridge, MA (US);
Wen Xue, Cambridge, MA (US);
Daniel G. Anderson, Framingham, MA (US);
Joseph R. Dorkin, Somerville, MA (US);
Tyler E. Jacks, Newton, MA (US);
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12N 15/85 (2006.01); C12N 15/86 (2006.01); C12N 7/00 (2006.01); C12N 15/88 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/102 (2013.01); A61K 48/005 (2013.01); C12N 7/00 (2013.01); C12N 15/85 (2013.01); C12N 15/86 (2013.01); C12N 15/88 (2013.01); C12N 2750/14143 (2013.01);
Abstract
The present disclosure relates to compositions and methods for modifying a gene sequence, and for systems for delivering such compositions. For example, the disclosure relates to modifying a gene sequence using a CRISPR-Cas9 or other nucleic acid editing system, and methods and delivery systems for achieving such gene modification, such as viral or non-viral delivery systems.