The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 14, 2018

Filed:

Mar. 06, 2015
Applicants:

Nippi, Incorporated, Tokyo, JP;

The University of Tokyo, Tokyo, JP;

Inventors:

Naoko Teramura, Tokyo, JP;

Katsumasa Iijima, Tokyo, JP;

Osamu Hayashida, Tokyo, JP;

Keisuke Tanaka, Tokyo, JP;

Shunji Hattori, Tokyo, JP;

Teru Okitsu, Tokyo, JP;

Shoji Takeuchi, Tokyo, JP;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/52 (2006.01);
U.S. Cl.
CPC ...
C12N 9/52 (2013.01); C12Y 304/24007 (2013.01);
Abstract

Recombinant collagenases with a stable specific activity and enzyme agents for cell and tissue dissociation such a recombinant are provided. The recombinant collagenase is derived from-derived collagenase is characterized by having, from the N terminus to the C terminus, a collagenase catalytic domain, a linker region sequence, and a prepeptidase C terminal domain, which-derived recombinant collagenase does not comprise at least the prepeptidase C terminal domain. The obtained recombinant collagenase has a high and stable specific activity.


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