The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 2018
Filed:
Dec. 19, 2013
Applicant:
Electronic Biosciences, Inc., San Diego, CA (US);
Inventors:
Geoffrey A. Barrall, San Diego, CA (US);
Eric N. Ervin, Salt lake City, UT (US);
Prithwish Pal, San Diego, CA (US);
Assignee:
ELECTRONIC BIOSCIENCES, INC., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/31 (2006.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
C07K 14/31 (2013.01); C12Q 1/6869 (2013.01); Y10T 436/143333 (2015.01);
Abstract
Provided herein are alpha hemolysin polypeptides comprising modified amino acid sequences that can reduce the rate of translocation of a polymer. Also provided herein are apparatuses and devices comprising modified hemolysin polypeptides. Also provided herein are methods of using modified alpha hemolysin proteins for use in characterizing and/or sequencing a polymer or for use as molecular sensors.