The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 2018
Filed:
Nov. 20, 2015
Intercept Pharmaceuticals, Inc., New York, NY (US);
André Steiner, Raubling, DE;
Heidi Waenerlund Poulsen, Køge, DK;
Emilie Jolibois, Cambridge, GB;
Melissa Rewolinski, San Diego, CA (US);
Ralf Gross, Raubling, DE;
Emma Sharp, Cambridge, GB;
Fiona Dubas-Fisher, Cambridge, GB;
Alex Eberlin, Cambridge, GB;
Intercept Pharmaceuticals, Inc., New York, NY (US);
Abstract
The present invention relates to obeticholic acid: or a pharmaceutically acceptable salt, solvate or amino acid conjugate thereof. Obeticholic acid is useful for the treatment or prevention of a FXR mediated disease or condition, cardiovascular disease or cholestatic liver disease, and for reducing HDL cholesterol, for lowering triglycerides in a mammal, or for inhibition of fibrosis. The present invention also relates to processes for the synthesis of obeticholic acid.