The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 14, 2018

Filed:

Nov. 23, 2015
Applicants:

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Petra Heinrich-keldenich, Wuppertal, DE;

Inventors:

Andreas Schall, Wuppertal, DE;

Jürgen Klar, Wuppertal, DE;

Mario Lobell, Wuppertal, DE;

Hartmut Schirok, Langenfeld, DE;

Joachim Telser, Wuppertal, DE;

Steffen Müller, Essen, DE;

Dirk Brohm, Mettmann, DE;

Hans Briem, Berlin, DE;

Hannah Jörißen, Heiligenhaus, DE;

Joerg Keldenich, Berlin, DE;

Michael Böttger, Wuppertal, DE;

Georges Von Degenfeld, Leverkusen, DE;

Thomas Schlange, Haan, DE;

Ulf Bömer, Glienicke, DE;

Niels Lindner, Wuppertal, DE;

Hanna Eilken, Wuppertal, DE;

Dmitrij Hristodorov, Wuppertal, DE;

Pierre Wasnaire, Düsseldorf, DE;

Kersten Matthias Gericke, Wuppertal, DE;

Lars Bärfacker, Düsseldorf, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/551 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); A61K 31/5513 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/5513 (2013.01); A61K 39/39558 (2013.01);
Abstract

The present application relates to novel (3-hydroxyphenyl)amino-substituted pyrido[2,3-b][1,5]benzodiazepin-5-one derivatives, to processes for preparation thereof, to the use thereof alone or in combination for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially of angiogenic disorders and hyperproliferative disorders in which neovascularization plays a role, for example ophthalmological disorders and cancers and tumours. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.


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