The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 2018
Filed:
Aug. 18, 2017
Applicant:
Natco Pharma Limited, Hyderabad, IN;
Inventors:
Amala Kompella, Hyderabad, IN;
Venugopala Krishna Gampa, Hyderabad, IN;
Srinivasulu Ganganamoni, Hyderabad, IN;
Balakrishna Reddy Sirigireddy, Hyderabad, IN;
Kali Satya Bhujanga Rao Adibhatla, Hyderabad, IN;
Venkaiah Chowdary Nannapaneni, Hyderabad, IN;
Assignee:
NATCO PHARMA LIMITED, Hyderabad, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01);
Abstract
The present invention relates to novel antiproliferative 1H-1, 8-naphthyridin-2-ones of the general formula (I) or pharmaceutically acceptable salts thereof: In which the variable groups are as defined herein, and their preparation and use in therapeutic treatment of disorders related to inhibition of tyrosine kinases in warm blooded animals. The compounds can overcome imatinib induced drug resistance.