The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 14, 2018

Filed:

Sep. 15, 2014
Applicant:

Astrazeneca Ab, Sodertalje, SE;

Inventors:

Marianne Bernice Ashford, Macclesfield, GB;

James Martin Nolan, III, Cambridge, MA (US);

Eyoung Shin, Cambridge, MA (US);

Young-Ho Song, Cambridge, MA (US);

Greg Troiano, Cambridge, MA (US);

Hong Wang, Cambridge, MA (US);

Assignee:

ASTRAZENECA AB, Sodertalje, SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); C07D 403/12 (2006.01); A61K 47/12 (2006.01); A61K 9/51 (2006.01); A61K 31/675 (2006.01); A61K 45/06 (2006.01); A61K 31/517 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 9/0019 (2013.01); A61K 9/16 (2013.01); A61K 9/5123 (2013.01); A61K 9/5153 (2013.01); A61K 31/517 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); A61K 47/12 (2013.01);
Abstract

Described herein are polymeric nanoparticles that include a therapeutic agent which is 2-(3-((7-(3-(ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide (also known as AZD1152 hqpa) or a pharmaceutically acceptable salt thereof, and methods of making and using such therapeutic nanoparticles.


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