The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 14, 2018

Filed:

Oct. 22, 2014
Applicant:

Glytech, Inc., Kyoto, JP;

Inventors:

Yasuhiro Kajihara, Osaka, JP;

Yasuhito Morishita, Osaka, JP;

Takefumi Murase, Kyoto, JP;

Assignee:

GLYTECH, INC., Kyoto, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 13/22 (2006.01); C12P 13/02 (2006.01); C12N 9/10 (2006.01); C07C 319/28 (2006.01); C07B 57/00 (2006.01); C12P 41/00 (2006.01); C07C 319/02 (2006.01); C07H 21/04 (2006.01); C12N 9/80 (2006.01);
U.S. Cl.
CPC ...
C07C 319/28 (2013.01); C07B 57/00 (2013.01); C07C 319/02 (2013.01); C12P 13/222 (2013.01); C12P 13/225 (2013.01); C12P 41/001 (2013.01); C07B 2200/07 (2013.01); C12N 9/80 (2013.01);
Abstract

The object of the present invention is to provide a method of efficiently manufacturing an optically active D- and/or L-form amino acid possessing a thiol group in the side chain by a simple method. The present invention provides a method of manufacturing an amino acid derivative possessing a thiol group in the side chain, characterized in manufacturing an intermediate composition comprising D- and L-forms of an amino acid derivative possessing a thiol group at the β-position, reacting a hydrolase selective for D- or L-amino acids, and separating the hydrolyzed D- or L-amino acid derivative, as well as an intermediate thereof.


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