The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 14, 2018

Filed:

Dec. 09, 2014
Applicant:

Basf SE, Ludwigshafen, DE;

Inventors:

Tiziana Chiodo, Mannheim, DE;

Beate Salvador, Ellerstadt, DE;

Marcus Vossen, Limburgerhof, DE;

Andreas Hafner, Gelterkinden, CH;

Tobias Hintermann, Therwil, CH;

Martin Szelagiewicz, Basel, CH;

Fritz Blatter, Reinach, CH;

Martin Viertelhaus, Mannheim, DE;

Walter Weishaar, Gruenstadt, DE;

Assignee:

BASF SE, Ludwigshafen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/58 (2006.01); A61K 9/14 (2006.01); C07J 43/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/58 (2013.01); A61K 9/14 (2013.01); C07J 43/003 (2013.01); C07B 2200/13 (2013.01);
Abstract

Combinations of (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-yl acetate (Abiraterone acetate) with acidic substances such as citric acid, ascorbic acid, methyl-4-hydroxy benzoate, saccharin, vanillic acid, adipic acid, maleic acid, malic acid, tartaric acid are useful as pharmaceutical preparations and show improved properties such as aqueous solubility and dissolution kinetics, especially in the form of cocrystals or their combination with a suitable acid.


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