The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 2018
Filed:
Apr. 25, 2014
Tobira Therapeutics, Inc., South San Francisco, CA (US);
Mitsuru Shiraishi, Hyogo, JP;
Masanori Baba, Kagoshima, JP;
Katsuji Aikawa, Osaka, JP;
Naoyuki Kanzaki, Osaka, JP;
Masaki Seto, Osaka, JP;
Yuji Iizawa, Kyoto, JP;
TOBIRA THERAPEUTICS, INC., South San Francisco, CA (US);
Abstract
The present invention provides a new cyclic compound having a CCR antagonist activity, especially a CCR5 antagonist activity, and the use thereof. The compound of the present invention is represented by the formula: wherein, Ris a 5- to 6-membered ring group which may be substituted; Xis a bond or the like; ring A is a 5- to 6-membered ring group which may be substituted; ring B is a 8- to 10-membered ring group which may be substituted; Xis a bivalent group of 1 to 4 atom; Zis a bivalent cyclic ring group or the like; Zis a bond or the like; and Ris an amino group, a nitrogen-containing heterocyclic group which may be substituted or the like, or a salt thereof.