The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 07, 2018

Filed:

Jun. 04, 2015
Applicant:

Max-planck-gesellschaft Zur Förderung Der Wissenschaften E. V., München, DE;

Inventors:

Zoltán Konthur, Berlin, DE;

Hans Lehrach, Berlin, DE;

Karl Skriner, Berlin, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/573 (2006.01); G01N 33/68 (2006.01); G01N 33/564 (2006.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); G01N 33/564 (2013.01); G01N 33/68 (2013.01); G01N 33/6854 (2013.01); G01N 33/6863 (2013.01); G01N 2333/47 (2013.01); G01N 2333/4703 (2013.01); G01N 2333/705 (2013.01); G01N 2333/82 (2013.01); G01N 2333/916 (2013.01); G01N 2333/9121 (2013.01); G01N 2333/91171 (2013.01); G01N 2333/91205 (2013.01); G01N 2333/99 (2013.01); G01N 2800/10 (2013.01); G01N 2800/102 (2013.01); G01N 2800/52 (2013.01);
Abstract

The invention refers to a method for diagnosing an individual who is to be subjected to or is being subjected to an anti-tumor necrosis factor alpha (TNFα or TNF) treatment to assess the responsiveness to an anti-TNF treatment which comprises the detection of immunoglobulin(s) against one or more biomarker proteins in a bodily fluid or an excrement of said patient, and sorting the individual into one of two categories based on detection of said immunoglobulin(s), wherein individuals are classified as NON-responder or responder. The invention refers to diagnostic kits comprising said one or more biomarker proteins and the use of these kits for assessing the responsiveness to an anti-TNF treatment of an individual who is to be subjected to or is being subjected to an anti-TNFα treatment.


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