The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 07, 2018

Filed:

Apr. 03, 2017
Applicant:

Robert Bosch Gmbh, Stuttgart, DE;

Inventors:

Christopher Johnson, San Carlos, CA (US);

Sam Kavusi, Menlo Park, CA (US);

Nadezda Fomina, Fremont, CA (US);

Habib Ahmad, Sunnyvale, CA (US);

Autumn Maruniak, Fremont, CA (US);

Christoph Lang, Cupertino, CA (US);

Ashwin Raghunathan, San Francisco, CA (US);

Assignee:

ROBERT BOSCH GMBH, Stuttgart, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/416 (2006.01); C12Q 1/00 (2006.01); G01N 27/30 (2006.01); G01N 27/327 (2006.01);
U.S. Cl.
CPC ...
G01N 27/4167 (2013.01); C12Q 1/001 (2013.01); G01N 27/302 (2013.01); G01N 27/3275 (2013.01);
Abstract

Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.


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