The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 07, 2018

Filed:

Aug. 29, 2014
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Warren S. Grundfest, Los Angeles, CA (US);

Oscar M. Stafsudd, Los Angeles, CA (US);

Pei-Chi Jiang, Los Angeles, CA (US);

Asael Papour, Los Angeles, CA (US);

Zachary Deis Taylor, Poway, CA (US);

Maie St. John, Los Angeles, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01J 1/58 (2006.01); G01N 21/64 (2006.01); G02B 21/16 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6408 (2013.01); G01N 21/6428 (2013.01); G01N 21/6447 (2013.01); G01N 21/6458 (2013.01); G01N 21/6486 (2013.01); G02B 21/16 (2013.01); G01N 2021/6413 (2013.01); G01N 2021/6441 (2013.01); G01N 2201/062 (2013.01); G01N 2201/0621 (2013.01);
Abstract

A time-resolved fluorescence imaging (TRFI) system that images a target medium without lifetime fitting. Instead of extracting the lifetime precisely, the system images the fluorophore distribution to allow for a simple and accurate method to obtain the fluorescence image without lifetime-extraction for time-resolved fluorescence imaging. An illumination source circuit for TRFI is also disclosed that shapes the excitation pulse. In one embodiment, the illumination source comprises an LED and stub line configured for generating a linear decay profile.


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