The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 07, 2018

Filed:

Sep. 19, 2014
Applicants:

The Trustees of the Stevens Institute of Technology, Hoboken, NJ (US);

Hackensack University Medical Center, Hackensack, NJ (US);

Inventors:

Woo Young Lee, Lyndhurst, NJ (US);

Yexin Gu, North Bergen, NJ (US);

Qiaoling Sun, Secaucus, NJ (US);

Wenting Zhang, Kearny, NJ (US);

Jenny Zilberberg, Yardley, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12M 3/06 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0654 (2013.01); C12M 23/16 (2013.01); C12M 25/16 (2013.01); C12M 29/04 (2013.01); G01N 33/5026 (2013.01); G01N 33/5044 (2013.01); C12N 2531/00 (2013.01); C12N 2533/54 (2013.01);
Abstract

A bed of microbeads is used as a foundation for reconstructing a three-dimensional osteocyte network by culturing osteocytes within the bed. The osteocytes are cultured such that they form a network among the microbeads that is capable of simulating the osteocyte network of natural bone. The osteocytes are cultured in a microfluidic device adapted for the purpose.


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