The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2018
Filed:
Feb. 03, 2010
Applicants:
Hideyuki Okano, Tokyo, JP;
Yohei Okada, Tokyo, JP;
Masaya Nakamura, Tokyo, JP;
Inventors:
Assignee:
Keio University, Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/079 (2010.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0618 (2013.01); A61K 35/12 (2013.01); C12N 2501/115 (2013.01); C12N 2501/235 (2013.01); C12N 2506/45 (2013.01);
Abstract
A method for differentiating a human differentiated cell-derived pluripotent stem cell into a neural stem cell is provided, which includes the steps of: making an embryoid body from the human differentiated cell-derived pluripotent stem cell; and culturing the embryoid body in a medium containing LIF to differentiate into a neural stem cell, so that, when the neural stem cell is allowed to differentiate in vitro after multiple subculturing of the neural stem cell, it differentiate mainly into neurons but substantially not into glial cells.