The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2018
Filed:
Nov. 20, 2015
Medimmune, Llc, Gaithersburg, MD (US);
Partha S. Chowdhury, Gaithersburg, MD (US);
David Tice, Gaithersburg, MD (US);
Zhan Xiao, Boyds, MD (US);
Philipp Steiner, Washington, DC (US);
Krista Kinneer, Montgomery Village, MD (US);
Marlon Rebelatto, Gaithersburg, MD (US);
MEDIMMUNE, LLC, Gaithersburg, MD (US);
Abstract
The present invention relates to antibodies and antigen binding fragments thereof that bind the extracellular domain of the HER3 receptor and inhibit various HER3 receptor related functions via ligand-dependent and/or ligand-independent mechanisms. Also provided are compositions with increased half-life. In addition, the invention provides compositions and methods for diagnosing and treating diseases associated with HER3 mediated signal transduction.