The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 07, 2018

Filed:

Apr. 24, 2013
Applicant:

Isis Innovation Limited, Oxford, GB;

Inventors:

Daniel Clive Anthony, Oxford, GB;

Sandra Jane Campbell, Oxford, GB;

Francis Joseph Carr, Balmedie, GB;

Robin Patrick Choudhury, Oxford, GB;

Benjamin Guy Davis, Oxford, GB;

Timothy David Jones, Babraham, GB;

Nicola Ruth Sibson, Oxford, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); G01N 33/543 (2006.01); G01N 33/574 (2006.01); G01N 33/58 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2836 (2013.01); G01N 33/54346 (2013.01); G01N 33/57492 (2013.01); G01N 33/585 (2013.01); G01N 33/6872 (2013.01); G01N 33/6896 (2013.01); C07K 2317/92 (2013.01); G01N 2333/70542 (2013.01); G01N 2800/285 (2013.01);
Abstract

The invention provides an antibody or fragment thereof that specifically binds to human endothelial vascular cell adhesion molecule-1 (VCAM-1), wherein the antibody or fragment thereof binds to the extracellular domain of VCAM-1, and wherein the antibody or fragment thereof binds to VCAM-1 when expressed on endothelial cells, wherein the antibody or fragment thereof is a human or humanized antibody, or fragment thereof.


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