The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2018
Filed:
May. 27, 2015
Astrazeneca Ab, Sodertalje, SE;
Cancer Research Technology Limited, London, GB;
Maurice Raymond Verschoyle Finlay, Cambridge, GB;
Chukuemeka Tennyson Ekwuru, Cambridge, GB;
Mark David Charles, Cambridge, GB;
Piotr Antoni Raubo, Cambridge, GB;
Jonathan James Gordon Winter, Cambridge, GB;
Johannes Wilhelmus Maria Nissink, Cambridge, GB;
AstraZeneca AB, Sodertalje, SE;
Cancer Research Technology Limited, London, GB;
Abstract
The specification relates to compounds of Formula (I), and pharmaceutically acceptable salts thereof, where Q, R, Rand Rhave any of the meanings defined herein. The specification also relates to the use of such compounds and salts thereof to treat or prevent GLS1 mediated disease, including cancer. The specification further relates to crystalline forms of compounds of Formula (I) and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds and salts; kits comprising such compounds and salts; methods of manufacture of such compounds and salts; intermediates useful in the manufacture of such compounds and salts; and to methods of treating GLS1 kinase mediated disease, including cancer, using such compounds and salts.