The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2018
Filed:
May. 14, 2015
Peloton Therapeutics, Inc., Dallas, TX (US);
Darryl David Dixon, Somerset, NJ (US);
Jonas Grina, Coppell, TX (US);
John A. Josey, Dallas, TX (US);
James P. Rizzi, Irving, TX (US);
Stephen T. Schlachter, Dallas, TX (US);
Eli M. Wallace, Richardson, TX (US);
Bin Wang, Dallas, TX (US);
Paul Wehn, Dallas, TX (US);
Hanbiao Yang, Coppell, TX (US);
Peloton Therapeutics, Inc., Dallas, TX (US);
Abstract
Benzimidazole derivatives of Formula I, that modulate the activity of ACSS2 are disclosed for therapeutic use. The fused imidazole ring of the compounds disclosed has a diarylmethyl or diarylmethanol moiety attached at the 2-position and the as compounds have at least one other substituent at the 5 or 6 position of the benzimidazole. Also disclosed are methods of using the benzimidazole compounds for the treatment of diseases or disorders, such as cancer.