The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 07, 2018

Filed:

Oct. 01, 2015
Applicant:

Ocera Therapeutics, Inc., Palo Alto, CA (US);

Inventors:

Eric Marsault, Sherbrooke, CA;

Kamel Benakli, Blue Bell, PA (US);

Hamid Hoveyda, Brussels, BE;

Mark L. Peterson, Sherbrooke, CA;

Sylvie Beaubien, Sherbrooke, CA;

Luc Ouellet, Sherbrooke, CA;

Carl St-Louis, Sherbrooke, CA;

Sophie Beauchemin, Sherbrooke, CA;

Assignee:

Ocera Therapeutics, Inc., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 29/12 (2006.01); A61K 31/03 (2006.01); C07C 213/08 (2006.01); A61K 38/12 (2006.01); A61K 38/22 (2006.01); C07D 273/00 (2006.01); C07D 413/06 (2006.01); C07D 498/04 (2006.01); C07K 5/087 (2006.01); C07K 5/097 (2006.01); C07K 5/08 (2006.01); C07C 41/18 (2006.01); C07C 67/343 (2006.01);
U.S. Cl.
CPC ...
C07C 213/08 (2013.01); A61K 38/12 (2013.01); A61K 38/2214 (2013.01); C07C 41/18 (2013.01); C07C 67/343 (2013.01); C07D 273/00 (2013.01); C07D 413/06 (2013.01); C07D 498/04 (2013.01); C07K 5/0812 (2013.01); C07K 5/0821 (2013.01); C07K 5/0827 (2013.01);
Abstract

The present invention is directed to novel macrocyclic compounds of formula (I) and their pharmaceutically acceptable salts, hydrates or solvates: wherein R, R, R, R, R, R, n, m, p Z, Z, and Zare as described in the specification. The invention also relates to compounds of formula (I) which are antagonists of the motilin receptor and are useful in the treatment of disorders associated with this receptor and with or with motility dysfunction.


Find Patent Forward Citations

Loading…