The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2018
Filed:
Apr. 08, 2016
Applicant:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Inventors:
Eric G. Schmuck, Deforest, WI (US);
Kurt W. Saupe, Madison, WI (US);
Assignee:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/54 (2006.01); A61K 35/28 (2015.01); A61K 35/33 (2015.01); A61K 35/34 (2015.01); C12N 5/077 (2010.01); C12N 5/0775 (2010.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3633 (2013.01); A61K 35/28 (2013.01); A61K 35/33 (2013.01); A61K 35/34 (2013.01); A61L 27/3687 (2013.01); A61L 27/3834 (2013.01); A61L 27/54 (2013.01); C12N 5/0657 (2013.01); C12N 5/0663 (2013.01); A61K 38/00 (2013.01); A61L 2300/414 (2013.01); A61L 2430/20 (2013.01); C12N 2513/00 (2013.01); C12N 2533/90 (2013.01);
Abstract
A bioscaffold made from an isolated cardiac fibroblast-derived 3-dimensional extracellular matrix (ECM) is disclosed. The bioscaffold can be used as an epicardial patch for the delivery of therapeutic cells into myocardial tissue. Methods of making the 3-dimensional extracellular matrix using cultured cardiac fibroblasts are also disclosed.