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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10039786 B1

PDFFull Text
Date of Patent:
Aug. 07, 2018

Filed:

Jul. 12, 2013

Acellular pro-tolerogenic compositions and process for making same

Applicant:

Canadian Blood Services, Ottawa, CA;

Inventors:

Mark D. Scott, Surrey, CA;

Duncheng Wang, Greenville, NC (US);

Wendy M. Toyofuku, Surrey, CA;

Assignee:

CANADIAN BLOOD SERVICES, Ottawa, CA;

Attorney:

Norton Rose Fulbright US LLP

Primary Examiner:

Amy E Juedes

Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C07H 21/02 (2006.01); A61K 35/17 (2015.01); C12N 5/0783 (2010.01); A61K 39/00 (2006.01); C12N 15/113 (2010.01); A61K 9/00 (2006.01); A61K 35/14 (2015.01); A61K 47/48 (2006.01); A61K 35/00 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 9/0019 (2013.01); A61K 35/14 (2013.01); A61K 39/001 (2013.01); A61K 39/0008 (2013.01); A61K 47/48776 (2013.01); C12N 5/0637 (2013.01); C12N 5/0638 (2013.01); C12N 15/113 (2013.01); A61K 35/00 (2013.01); A61K 47/48215 (2013.01); A61K 2035/122 (2013.01); A61K 2035/124 (2013.01); A61K 2039/515 (2013.01); A61K 2039/577 (2013.01); C12N 2310/141 (2013.01); C12N 2500/50 (2013.01); C12N 2501/00 (2013.01); C12N 2501/65 (2013.01); C12N 2502/1114 (2013.01);
Abstract

This invention relates to pro-tolerogenic preparations capable of increasing the level of regulatory T cells (Treg) and/or decreasing the level of pro-inflammatory T cells (Th17) to induce anergy or immune tolerance. The pro-tolerogenic preparation is enriched in at least one species of miRNAs and is obtained by contacting two allogeneic leukocyte populations wherein at least one of the two populations is modified with a low-immunogenic biocompatible polymer. Acellular pro-tolerogenic compositions, process for making such composition as well as therapeutic uses of such compositions are also provided.

Find Patent Forward Citations

Scott, Mark. (2018). Acellular pro-tolerogenic compositions and process for making same (U.S. Patent No. 10039786). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10039786

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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