The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2018
Filed:
Apr. 18, 2016
Applicant:
Stc.unm, Albuquerque, NM (US);
Inventors:
Alexandre Chigaev, Santa Fe, NM (US);
Larry A. Sklar, Albuquerque, NM (US);
Dominique Perez, Albuquerque, NM (US);
Assignee:
STC.UNM, Albuquerque, NM (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/12 (2015.01); A61K 31/58 (2006.01); A61K 31/47 (2006.01); A61K 31/122 (2006.01); G01N 33/50 (2006.01); A61K 31/4425 (2006.01); A61K 31/357 (2006.01); A61K 31/343 (2006.01); A61K 31/35 (2006.01); A61K 31/437 (2006.01); A61K 31/00 (2006.01); A61K 31/365 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/58 (2013.01); A61K 31/00 (2013.01); A61K 31/122 (2013.01); A61K 31/343 (2013.01); A61K 31/35 (2013.01); A61K 31/357 (2013.01); A61K 31/365 (2013.01); A61K 31/437 (2013.01); A61K 31/4425 (2013.01); A61K 31/47 (2013.01); A61K 45/06 (2013.01); G01N 33/5011 (2013.01); G01N 2500/10 (2013.01); G01N 2800/52 (2013.01);
Abstract
In one embodiment, the invention provides a method of inhibiting cAMP efflux and increasing intracellular cAMP in a subject who suffers from, or who is at risk of developing, a cancer by administering to the subject a therapeutically-effective amount of a cAMP efflux inhibitor. Novel compounds, pharmaceutical compositions, diagnostics and screening methods are also provided.