The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2018
Filed:
Oct. 23, 2015
Applicant:
Keck Graduate Institute of Applied Life Sciences, Claremont, CA (US);
Inventors:
Mikhail Martchenko, Claremont, CA (US);
Leeor Zilbermintz, Encino, CA (US);
William Leonardi, Rosemead, CA (US);
Assignee:
Keck Graduate Institute of Applied Life Sciences, Claremont, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4706 (2006.01); A61K 31/131 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4706 (2013.01); A61K 31/131 (2013.01); A61K 45/06 (2013.01);
Abstract
Compositions and methods including Amodiaquine (AQ) or N-Desethy Amodiaquine (DEAQ) are provided for treating, inhibiting, or preventing cathepsin B dependent pathogens and toxins in a host cell or infected subject. Compositions and methods also include AQ or DEAQ in combination with an antibiotic for more effective clearance of the pathogen and/or toxins.