The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2018
Filed:
Dec. 10, 2013
Agency for Science, Technology and Research, Singapore, SG;
Nanyang Technological University, Singapore, SG;
David Paramelle, Singapore, SG;
Nikodem Tomczak, Singapore, SG;
Paul Free, Singapore, SG;
Sierin Lim, Singapore, SG;
Tao Peng, Singapore, SG;
Agency for Science, Technology, and Research, Singapore, SG;
Nanyang Technological University, Singapore, SG;
Abstract
The invention relates to a method to encapsulate nanoparticles into a protein cage by inserting the nanoparticles into the core through holes. Currently commercially available nanoparticles can be functionalized using the inventive method. The inventive hybrids have applications in biosensing and bioimaging. The use of an affinity between poly-histidine chains and nitrilotriacetic acid as chelating reagent to obtain the inventive cages and hybrid assemblies by the method according to the invention is shown in FIG.