The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2018
Filed:
Oct. 02, 2014
Applicant:
The Rockefeller University, New York, NY (US);
Inventors:
W. Vallen Graham, New York, NY (US);
Thomas P. Sakmar, New York, NY (US);
Assignee:
THE ROCKEFELLER UNIVERSITY, New York, NY (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C07K 16/18 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 49/0004 (2013.01); C07K 14/4711 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01);
Abstract
The invention relates to methods for obtaining antibodies that recognize amyloid protofibrils and antibodies that recognize one or more amyloid protofibrils. Also provided are methods of using the antibodies to prevent or inhibit amyloid disease in a subject, to diagnose amyloid disease in a subject, and to detect amyloid protofibrils in a sample.