The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2018
Filed:
Jul. 28, 2016
Applicant:
Bayer Healthcare Llc, Whippany, NJ (US);
Inventors:
Richard Feldman, El Cerrito, CA (US);
Ji-Yun Kim, Berkeley, CA (US);
Haiyan Jiang, San Francisco, CA (US);
Kirk McLean, Orinda, CA (US);
Junliang Pan, Moraga, CA (US);
Glenn Pierce, La Jolla, CA (US);
James Wu, El Cerrito, CA (US);
Xiao-Yan Zhao, Union City, CA (US);
Assignee:
Bayer HealthCare LLC, Whippany, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/755 (2006.01); A61K 38/37 (2006.01); A61K 38/48 (2006.01); C07K 16/28 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/755 (2013.01); A61K 38/37 (2013.01); A61K 38/4846 (2013.01); C07K 16/2839 (2013.01); A61K 38/00 (2013.01); C07K 2317/622 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01);
Abstract
Targeted coagulation factors comprising a coagulation factor linked with at least one domain that specifically binds to a membrane protein on a blood cell is provided. The disclosed targeted coagulation factors increase the efficiency of coagulation factors and prolong their duration of action and thus, are an improvement for the treatment of hematological diseases such as hemophilia A.