The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2018
Filed:
Oct. 04, 2013
Applicant:
Immunogen, Inc., Waltham, MA (US);
Inventors:
Xiaoxi Kevin Chen, Natick, MA (US);
Xinfang Li, Newton, MA (US);
Assignee:
IMMUNOGEN, INC., Waltham, MA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 51/10 (2006.01); C07K 16/00 (2006.01); C07K 1/34 (2006.01); B01D 71/34 (2006.01); B01D 15/26 (2006.01); B01D 15/32 (2006.01); B01D 15/36 (2006.01); B01D 15/38 (2006.01); C07K 1/18 (2006.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
C07K 1/18 (2013.01); A61K 47/6817 (2017.08); B01D 15/265 (2013.01); B01D 15/325 (2013.01); B01D 15/327 (2013.01); B01D 15/361 (2013.01); B01D 15/3804 (2013.01); B01D 71/34 (2013.01);
Abstract
The invention provides processes for preparing purified cell-binding agent cytotoxic agent conjugates comprising subjecting a mixture comprising a cell-binding agent cytotoxic agent conjugate and one or more impurities to a polyvinyl difluoride (PVDF) membrane to remove at least a portion of the impurities from the mixture, thereby providing a purified cell-binding agent cytotoxic agent conjugate.