The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 31, 2018

Filed:

Jan. 22, 2016
Applicant:

Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Lianyungang, CN;

Inventors:

Shuhui Chen, Shanghai, CN;

Charles Z. Ding, Shanghai, CN;

Xiaobing Yan, Shanghai, CN;

Wei Huang, Shanghai, CN;

Guoping Hu, Shanghai, CN;

Jian Li, Shanghai, CN;

Xiquan Zhang, Lianyungang, CN;

Ling Yang, Lianyungang, CN;

Hongjiang Xu, Lianyungang, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01); C07D 487/08 (2006.01); C07D 495/04 (2006.01); C07D 487/04 (2006.01); C07D 417/04 (2006.01); C07D 471/04 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 487/08 (2013.01); C07D 495/04 (2013.01);
Abstract

The present invention relates to a compound represented by formula (I) of a resorcinol derivative as an HSP90 inhibitor or pharmaceutically accepted salts thereof. The compound in the present invention has the activity of inhibiting heat shock protein HSP90. Therefore, the compound in the present invention is used to treat proliferative diseases such as cancer and neurodegenerative diseases. The present invention further provides the compounds and preparation methods for pharmaceutical compositions comprising the compounds, a method for treating diseases, and pharmaceutical compositions comprising the compounds.


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