The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2018
Filed:
Oct. 17, 2013
Bristol-myers Squibb Company, Princeton, NJ (US);
Exelixis, Inc., South San Francisco, CA (US);
Wei Xu, Danville, CA (US);
Yong Wang, Foster City, CA (US);
Sunghoon Ma, Foster City, CA (US);
Elena S. Koltun, Foster City, CA (US);
Byung Gyu Kim, Daejeon, KR;
Joon Won Jeong, Belmont, CA (US);
T. G. Murali Dhar, Princeton, NJ (US);
Lynne Canne Bannen, Pacifica, CA (US);
Exelixis, Inc., Alameda, CA (US);
Bristol-Myers Squibb Co., New York, NY (US);
Abstract
Described are RORy modulators of the formula (I), and N-oxides thereof, and pharmaceutically acceptable salts thereof, and solvates and hydrates thereof, wherein R, R, R, R, R, R, R, x, y, L, G, Z, the bond denoted by 'q', the ring system denoted by 'A' and the ring system denoted by “B” are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORy activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORy activity, for example, autoimmune and/or inflammatory disorders.