The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2018
Filed:
Dec. 22, 2014
Applicant:
The Johns Hopkins University, Baltimore, MD (US);
Inventors:
Jonathan Powell, Baltimore, MD (US);
Ying-Chun Lo, Baltimore, MD (US);
Michael Edidin, Baltimore, MD (US);
Assignee:
THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 39/00 (2006.01); A61K 47/69 (2017.01); A61K 47/68 (2017.01); A61K 39/39 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 39/39 (2013.01); A61K 47/48561 (2013.01); A61K 47/48884 (2013.01); A61K 47/6849 (2017.08); A61K 47/6929 (2017.08); C12N 5/0636 (2013.01); C12N 5/0638 (2013.01); A61K 2039/55516 (2013.01); C12N 2501/515 (2013.01); C12N 2501/599 (2013.01); C12N 2531/00 (2013.01);
Abstract
The presently disclosed subject matter provides methods and compositions for activation of clustered receptors on a target cell using nanocarrier-associated ligands, particularly methods and compositions for targeted activation of clustered receptors on antigen-experienced T cells using nanocarrier-associated antibodies.