The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 31, 2018

Filed:

Jun. 12, 2013
Applicant:

Regenerative Research Foundation, Rensselaer, NY (US);

Inventors:

Sally Temple, Slingerlands, NY (US);

Jeffrey Stern, Slingerlands, NY (US);

Enrique L. Salero-Coca, Delmar, NY (US);

Assignee:

Regenerative Research Foundation, Rensselaer, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 5/0797 (2010.01); C12N 5/0735 (2010.01); C12N 5/074 (2010.01); C12N 5/0793 (2010.01); C12N 5/071 (2010.01); C12N 5/07 (2010.01); C12N 5/16 (2006.01); G01N 33/567 (2006.01); A01N 1/00 (2006.01); A01N 63/00 (2006.01); A61K 38/18 (2006.01); C12N 5/079 (2010.01);
U.S. Cl.
CPC ...
A61K 38/1825 (2013.01); C12N 5/0607 (2013.01); C12N 5/0619 (2013.01); C12N 5/0621 (2013.01); C12N 2501/115 (2013.01); C12N 2501/119 (2013.01); C12N 2501/385 (2013.01); C12N 2501/41 (2013.01); C12N 2506/02 (2013.01); C12N 2506/08 (2013.01); C12N 2533/52 (2013.01);
Abstract

The present invention relates to a retinal pigment epithelial stem cell isolated from a posterior region of the retinal pigment epithelium of an adult mammal. The invention also relates to a method of inducing differentiation of retinal epithelial stem and progenitor cells in vitro, wherein the cells of the invention are highly plastic, multipotential stem cells. The invention also includes methods for the treatment of retinal diseases and vision loss involving the transplantation of retinal pigment epithelial stem cells or cells differentiated from retinal pigment epithelial stem cells to the retina of a patient in need of treatment.


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