The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2018
Filed:
Apr. 13, 2015
Applicant:
Psioxus Therapeutics Limited, Oxfordshire, GB;
Inventors:
Leonard Charles William Seymour, Oxford, GB;
Alice Claire Noel Brown, Oxfordshire, GB;
Brian Robert Champion, Oxfordshire, GB;
Assignee:
PSIOXUS THERAPEUTICS LIMITED, Oxfordshire, GB;
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 35/761 (2015.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/761 (2013.01); C12N 7/00 (2013.01); A61K 2039/5256 (2013.01); C12N 2710/10321 (2013.01); C12N 2710/10332 (2013.01); C12N 2710/10343 (2013.01);
Abstract
The present disclosure relates to a type B adenovirus wherein E4orf4 is deleted or non-functional and generally having a DNA sequence in the E3 region, in particular viruses of formula (I), compositions containing the virus, for example pharmaceutical formulations of the virus, processes for making the viruses and the compositions and use of any one of the same in treatment, particularly in the treatment of cancer, such as colorectal cancer and ovarian cancer.5'ITR-B-B-B-B-B-B-B-3′ITR  (I).