The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2018

Filed:

Aug. 21, 2013
Applicant:

Cambridge Research & Instrumentation, Inc., Hopkinton, MA (US);

Inventor:

Clifford C. Hoyt, Wellesley, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06K 9/00 (2006.01); G01N 1/30 (2006.01); G01N 21/64 (2006.01); G02B 21/36 (2006.01); G06T 7/90 (2017.01);
U.S. Cl.
CPC ...
G06K 9/00127 (2013.01); G01N 1/30 (2013.01); G01N 21/6428 (2013.01); G01N 21/6456 (2013.01); G02B 21/365 (2013.01); G06T 7/90 (2017.01); G01N 21/6458 (2013.01); G01N 2021/6417 (2013.01); G01N 2021/6441 (2013.01); G01N 2021/6471 (2013.01); G06T 2207/10016 (2013.01); G06T 2207/10024 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/10064 (2013.01); G06T 2207/10152 (2013.01); G06T 2207/30024 (2013.01);
Abstract

The disclosure features methods and systems that include a detector configured to obtain multiple images of a sample stained with first and second stains, where the first and second stains have similar spectral absorption and emission profiles, and an electronic processor configured to decompose the multiple images into an unmixed image set, where the unmixed image set includes a first unmixed image corresponding to the first stain and a second unmixed image corresponding to the second stain, and identify nuclear regions in the sample based on the first unmixed image and identify cytoplasm regions in the sample based on the second unmixed image.


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