The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2018

Filed:

Jul. 10, 2015
Applicant:

Nederlandse Organisatie Voor Toegepast-natuurwetenschappelijk Onderzoek Tno, s'-Gravenhage, NL;

Inventors:

Dolf Jaap Klomp, 's-Gravenhage, NL;

Fokko Pieter Wieringa, 's-Gravenhage, NL;

Andrew Statham, 's-Gravenhage, NL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/25 (2006.01); G01N 21/71 (2006.01); G01N 21/05 (2006.01); G01N 21/85 (2006.01); G01N 33/487 (2006.01); A61B 5/1455 (2006.01); A61B 5/145 (2006.01); A61M 1/16 (2006.01); A61M 1/36 (2006.01);
U.S. Cl.
CPC ...
G01N 21/718 (2013.01); A61B 5/14546 (2013.01); A61B 5/14557 (2013.01); A61M 1/1605 (2014.02); A61M 1/3609 (2014.02); G01N 21/05 (2013.01); G01N 21/85 (2013.01); G01N 33/4875 (2013.01); A61M 2205/3306 (2013.01); G01N 2201/0686 (2013.01);
Abstract

A spectroscopy device is disclosed for inline monitoring of analytes in bulk fluid streams, capable of maintaining sterile conditions. The device comprises a cassette suitable for holding a fluid analyte () and having a laser entry wall part and a detector wall part, the laser entry wall part arranged to be optically transparent to laser radiation of a predetermined wavelength and the detector wall part arranged to be optically transparent for spectral parts of interest. Laser transmission optics are provided to focus a laser beam to produce a breakdown plasma discharge within the fluid inside the cassette. A photodetector substrate is provided comprising an array of photosensors, tuned to detect characteristic emission lines from the plasma. The photodetector substrate is conformal to at least the detector wall part of the cassette. A placement provision is arranged for user removable placement of the cassette. Dichroic hot and cold mirrors are applied to selectively transmit/reflect excitation laser light and light emitted by the plasma.


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